Resources
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PRESENTATIONS
APPLICATIONS and TOOLS
CLL calculator:
Application for Risk Assessment of Patients with Chronic Lymphocytic Leukemia
| Project Name: | Impact of functional polymorphisms influencing inflammation and oxidative stress on outcome and selection of treatment in chronic lymphocytic leukemia. |
| Project Number: | AZV 16-32339A (P03) |
| Authors: | Gajdoš Petr, Běhálek Marek, Kriegová Eva, Schneiderová Petra |
| Type: | standalone desktop application, windows10 |
| Resource: | This resource is available after sign in. In case you have no credentials, send a request to the contact e-mail. |
This software tool is used to calculate statistically significant rules over the data collection. It is assumed that the input file will contain the binary values of the attributes (DNA snips) of individual patients obtained during the examination. The outcome is represented by an evaluation of the chances of occurrence of the disease / complication. The tool supports the deciding making process whether to start or change the course of treatment.
OLGEN Coverage Limit calculator
| Project Name: | Impact of functional polymorphisms influencing inflammation and oxidative stress on outcome and selection of treatment in chronic lymphocytic leukemia. |
| Project Number: | AZV 16-32339A (P03) |
| Authors: | Vašinek Michal, Novosád Tomáš, Petráčková Anna, Kriegová Eva |
| Type: | web application |
| Resource: |
The software allows to calculate the required coverage depth of the sequenced DNA segment to detect somatic mutations in the human genome. The software implements a newly designed probability model that calculates the required sequence coverage depth for a given n-percent somatic mutation and a defined error rate of measurement.